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Related Experiment Video

Updated: Jun 27, 2026

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits

Published on: December 27, 2013

Approaching Visual Perception with Spatiotemporally Patterned Optogenetic Stimulation.

Amira K Fadl^1,2, Jackson J Cone^1,2,3

¹1Department of Biomedical Engineering, University of Calgary, Calgary, Alberta, Canada;

Annual Review of Vision Science

|June 25, 2026

Summary

This summary is machine-generated.

Optogenetic stimulation precisely manipulates neural activity, advancing our understanding of how visual brain regions process visual information and guide behavior. This technique is key to decoding perception.

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Last Updated: Jun 27, 2026

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits

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Published on: December 27, 2013

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

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In vivo Optogenetic Stimulation of the Rodent Central Nervous System

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Published on: January 15, 2015

Area of Science:

Neuroscience
Computational Neuroscience
Systems Neuroscience

Background:

Visual perception arises from complex neural activity patterns in the brain.
Understanding the causal link between specific neural activity and perception is a major challenge.
Traditional methods for perturbing neural activity lack the necessary spatiotemporal precision.

Purpose of the Study:

To review advances in optogenetic tools for precise neural manipulation.
To discuss the application of patterned optogenetic stimulation in behaving subjects.
To highlight future directions in using optogenetics to study visual perception.

Main Methods:

Survey of optical tools for optogenetic perturbations in mice and monkeys.
Analysis of patterned optogenetic experiments in behaving subjects.
Review of studies causally linking neural activity to perception.

Main Results:

Optogenetic stimulation allows for precise control over neural activity at relevant spatiotemporal scales.
Patterned optogenetic stimulation has provided significant insights into the neural basis of perception.
These methods enable causal testing of neural mechanisms underlying visual processing.

Conclusions:

Optogenetics offers unprecedented precision for investigating neural computations in perception.
Future research will likely leverage these advanced techniques to further unravel the neural basis of visual experience.
This approach is crucial for understanding how the brain constructs our visual world.