Paracentral acute middle maculopathy vs acute macular neuroretinopathy: A 2-case report

Although the exact etiology of paracentral acute middle maculopathy (PAMM) and acute macular neuroretinopathy (AMN) remains uncertain, several characteristic features have been identified. Advances in multimodal imaging have demonstrated a shared pathophysiological hallmark: retinal capillary ischemia. Both conditions involve impaired venous drainage, resulting in secondary ischemia localized to the deep capillary plexus. Although currently classified as distinct clinical entities, PAMM and AMN share significant similarities and may occasionally overlap or coexist. We report two clinical cases, one of PAMM and one of AMN, to highlight their principal similarities and differences.