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Updated: Jun 27, 2026

Isolation of Leukocytes from the Human Maternal-fetal Interface
Published on: May 21, 2015
[Advances in aberrant crosstalk among key immune cells at the maternal-fetal interface in recurrent spontaneous
Xiaoxiao Su1, Yujing Xiong1, Xiaohong Wang2
1Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China.
Abstract:
Recurrent spontaneous abortion (RSA) is a common pregnancy complication in women of reproductive age. Immune homeostasis at the maternal-fetal interface, maintained by various immune cells and cytokines, is crucial for normal pregnancy. Aberrant immune cell crosstalk disrupts this balance, potentially leading to adverse pregnancy outcomes. This review summarizes the mechanisms of RSA induced by key immune cells and recent advances in dysregulated immune cell interactions at the maternal-fetal interface.
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