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Enhanced urine refractive index sensing using a defect-engineered one-dimensional photonic crystal
1TH-PPM Group, Physics Department, Faculty of Science, Beni-Suef University, Beni Suef, 62111, Egypt. arafaaly@aucegypt.edu.
Scientific Reports
|June 25, 2026
Summary
A novel defect-engineered one-dimensional photonic crystal (1D PhC) sensor offers high-resolution urine refractive index detection. This sensor demonstrates excellent sensitivity and robustness for biomedical applications.
Area of Science:
- Photonics
- Biomedical Sensing
- Materials Science
Background:
- Photonic crystal (PhC) sensors offer label-free detection capabilities.
- Accurate refractive index (RI) measurement is crucial for biomedical diagnostics, particularly for urine analysis.
- Existing PhC sensors may face challenges in sensitivity, stability, or fabrication robustness.
Purpose of the Study:
- To propose and analyze a defect-engineered one-dimensional photonic crystal (1D PhC) sensor for high-resolution urine refractive index detection.
- To evaluate the sensor's performance metrics including sensitivity, linearity, Q-factor, and figure of merit (FOM).
- To assess the sensor's robustness against fabrication variations.
Main Methods:
- Numerical simulation using the transfer matrix method (TMM) to model the 1D PhC structure.
- Design incorporates alternating TiO₂/MgF₂ layers with a central defect cavity for urine analyte.
- Analysis of defect mode shift, Full Width at Half Maximum (FWHM), Q-factor, and FOM under varying RI and thickness perturbations.
Main Results:
- The proposed 1D PhC sensor exhibits a sharp localized resonance within the photonic band gap.
- A stable red shift of the defect mode was observed with increasing urine refractive index (1.333 to 1.360).
- Achieved high sensitivity (388.57 nm/RIU), excellent linearity, narrow linewidth (avg. FWHM of 0.0305 nm), high Q-factor, and FOM. Tolerance analysis confirmed good fabrication robustness with ±2.5% thickness variation.
Conclusions:
- The defect-engineered 1D PhC sensor demonstrates a promising, balanced performance for practical urine-based biomedical sensing.
- Sensor performance evaluation requires a holistic approach, considering sensitivity alongside linewidth, Q-factor, FOM, and fabrication tolerance.
- The proposed design offers a competitive alternative to existing photonic-crystal sensing platforms.

