Related Experiment Video
Updated: Jun 27, 2026

Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis
Published on: July 12, 2011
Renal Vein Thrombosis: A Narrative Review
Nicoletta Riva1, Alexander Gatt1, Maria Angela Gauci2
1Department of Pathology, Faculty of Medicine and Surgery, University of Malta, MSD 2080 Msida, Malta.
Renal venous thrombosis (RVT) is a rare condition affecting males more often, with distinct causes and symptoms in neonates and adults. Treatment focuses on anticoagulation, with varying outcomes and potential long-term complications.
Area of Science:
- Nephrology
- Vascular Medicine
- Pediatric Nephrology
Background:
- Renal venous thrombosis (RVT) is an uncommon site for venous thromboembolism.
- RVT exhibits a bimodal age distribution, affecting neonates and adults distinctly.
- Key risk factors include abdominal malignancies and nephrotic syndrome in adults, and sepsis or prematurity in children.
Purpose of the Study:
- To review current evidence on renal venous thrombosis (RVT).
- Focus on anticoagulant prophylaxis and treatment strategies.
- Analyze clinical outcomes in both adult and pediatric populations.
Main Methods:
- Narrative review of existing literature on RVT.
- Synthesis of data on risk factors, symptoms, and diagnostic approaches.
- Evaluation of treatment modalities including anticoagulation and endovascular procedures.
Main Results:
- Common symptoms include abdominal pain and hematuria; neonates may present with a palpable mass.
- Bilateral RVT can precipitate acute kidney injury.
- Anticoagulation is the primary treatment, with emerging use of direct oral anticoagulants.
Conclusions:
- RVT management requires tailored approaches based on age and clinical presentation.
- While pediatric mortality is low, long-term complications like kidney atrophy can occur.
- Adult RVT outcomes are influenced by comorbidities, with potential for high mortality.
Related Concept Videos
Venous Thrombosis I: Introduction
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Venous Thrombosis IV: Nursing Management
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Pulmonary Embolism III: Nursing Management
