Related Experiment Video
Updated: Jun 27, 2026
08:49
Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
A Rare Adult Ileal Intussusception Caused by Perineurioma
Yoen Young Chuah1,2, Seng-Wei Ooi3, Shih-Peng Hsieh4
1Department of Biological Science, College of Sciences, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.
Diagnostics (Basel, Switzerland)
|June 26, 2026
Summary
Adult intussusception, though rare, often signals an underlying issue. This case details ileal perineurioma, an unusual tumor causing small-bowel obstruction, emphasizing its diagnosis through histopathology.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- Adult intussusception is infrequent and typically necessitates identifying a pathological lead point.
- Ileal perineurioma, a rare benign peripheral nerve sheath tumor, has scarce reports in the gastrointestinal tract.
Purpose of the Study:
- To report a case of adult ileal intussusception caused by a rare perineurioma.
- To highlight the diagnostic challenges and definitive evaluation methods for this condition.
Main Methods:
- A 59-year-old woman presented with symptoms of small-bowel obstruction.
- Diagnosis involved contrast-enhanced computed tomography and subsequent emergency laparotomy with segmental resection.
- Histopathological and immunohistochemical analyses were crucial for definitive diagnosis.
Main Results:
- Computed tomography revealed ileal intussusception and small-bowel obstruction.
- Surgical resection confirmed ileal intussusception.
- Histopathology identified a spindle-cell neoplasm consistent with perineurioma, confirmed by positive epithelial membrane antigen (EMA) and Glucose Transporter-1 (GLUT-1) staining.
- The patient experienced an uneventful postoperative recovery with no recurrence.
Conclusions:
- Ileal perineurioma is a rare but significant differential diagnosis for adult small-bowel intussusception.
- Definitive diagnosis relies on thorough histopathological and immunohistochemical examination.
- Surgical management and follow-up are essential for favorable outcomes.
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