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Updated: Jun 27, 2026

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
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A Compositional Calibration Framework for Multi-Channel Functional Electrical Stimulation Enabling Hand Gesture

Elena Stefanel1, Nicolò Landra1, Andrea Prestia1

  • 1Department of Electronics and Telecommunications, Politecnico di Torino, 10129 Turin, Italy.

Bioengineering (Basel, Switzerland)
|June 26, 2026
PubMed
Summary

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This summary is machine-generated.

This study introduces a new framework for functional electrical stimulation (FES) to improve hand movement restoration. The compositional calibration method successfully combines individual finger movements for better hand function control.

Area of Science:

  • Rehabilitation Engineering
  • Neuroprosthetics
  • Biomechanics

Background:

  • Restoring hand motor function with functional electrical stimulation (FES) is challenging due to difficulties in calibrating multi-channel stimulation for coordinated movements.
  • Existing methods struggle to precisely control individual finger actions and combine them into functional gestures.

Purpose of the Study:

  • To propose and validate a compositional FES calibration framework for customizing isolated finger actions and combining them into functional hand gestures.
  • To assess the effectiveness of this framework in achieving coordinated multi-finger control.

Main Methods:

  • A two-session experimental study involving 13 participants.
  • Session 1: Subject-specific stimulation sites and parameters identified for 8 individual finger movements using a spatial grid.
Keywords:
calibrationfunctional electrical stimulationhand rehabilitationmulti-channel stimulation

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  • Session 2: Combination of isolated movements to generate 7 hand gestures in 5 participants.
  • Main Results:

    • 10 out of 13 participants achieved at least 6 movements; 3 achieved all targeted motions.
    • Individual finger movements were generally well-isolated, with challenges noted for thumb and ring/little finger extensions.
    • Individually calibrated activations successfully combined to produce coordinated multi-finger movements matching expected patterns.

    Conclusions:

    • Preliminary results support compositional calibration strategies for achieving functional multi-finger control with multi-channel FES.
    • This approach offers a promising avenue for enhancing hand function restoration in individuals with motor impairments.