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Related Concept Videos

Nuclear Transmutation03:20

Nuclear Transmutation

Nuclear transmutation is the conversion of one nuclide into another. It can occur by the radioactive decay of a nucleus, or the reaction of a nucleus with another particle. The first manmade nucleus was produced in Ernest Rutherford’s laboratory in 1919 by a transmutation reaction, the bombardment of one type of nuclei with other nuclei or with neutrons. Rutherford bombarded nitrogen-14 atoms with high-speed α particles from a natural radioactive isotope of radium and observed protons being...
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Many heavier elements with smaller binding energies per nucleon can decompose into more stable elements that have intermediate mass numbers and larger binding energies per nucleon—that is, mass numbers and binding energies per nucleon that are closer to the “peak” of the binding energy graph near 56. Sometimes neutrons are also produced. This decomposition of a large nucleus into smaller pieces is called fission. The breaking is rather random with the formation of a large number of different...
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Nuclear Fusion02:45

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Nuclear Power02:36

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Nuclear Fuels
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Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
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VITA Accelerator Neutron Sources: Status and Research Results.

Sergey Taskaev1,2, Evgenii Berendeev1,2, Marina Bikchurina1,2

  • 1Budker Institute of Nuclear Physics, Novosibirsk 630090, Russia.

Cancers
|June 26, 2026
PubMed
Summary
This summary is machine-generated.

Researchers developed the VITA accelerator neutron source for boron neutron capture therapy (BNCT). This system enables advanced dosimetry and shows promise for lithium neutron capture therapy, offering a more effective cancer treatment approach.

Keywords:
beam shaping assemblyboron delivery drugboron neutron capture therapycharged particle acceleratordosimetryneutron producing targetneutron source

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Area of Science:

  • Medical Physics
  • Nuclear Engineering
  • Oncology

Background:

  • Boron neutron capture therapy (BNCT) is a promising cancer treatment modality.
  • Development of efficient and reliable neutron sources is crucial for BNCT advancement.

Purpose of the Study:

  • To create an accelerator-based neutron source specifically for BNCT.
  • To develop advanced dosimetry tools and methods for precise radiation measurement.

Main Methods:

  • Designed and manufactured an accelerator neutron source (VITA facility).
  • Investigated charged particle transport and acceleration.
  • Developed and implemented novel dosimetry tools for boron, gamma, and neutron dose measurements.

Main Results:

  • The VITA facility, featuring a 2.3 MeV proton beam and lithium target, was successfully established.
  • VITA facilities are operational for research and clinical trials in multiple locations.
  • Demonstrated the efficacy of prompt gamma-ray spectroscopy for boron imaging and introduced lithium neutron capture therapy.

Conclusions:

  • The VITA facility is highly efficient, reliable, and compact.
  • Prompt gamma-ray spectroscopy is recommended for BNCT treatments.
  • Lithium neutron capture therapy, alone or combined with BNCT, shows significant therapeutic potential.