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Related Concept Videos

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...

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In Vivo Modeling of the Morbid Human Genome using Danio rerio
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Special Issue "Using Model Organisms to Study Complex Human Diseases".

Roberto Piergentili1

  • 1Istituto di Biologia e Patologia Molecolari (IBPM) del Consiglio Nazionale delle Ricerche (CNR), at Dipartimento di Biologia e Biotecnologie, Università Sapienza di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy.

International Journal of Molecular Sciences
|June 26, 2026
PubMed
Summary
This summary is machine-generated.

Model organisms are species used to study biological problems, enabling discoveries applicable to other species. These model systems provide insights into fundamental biological processes across diverse life forms.

Area of Science:

  • Biology
  • Genetics
  • Developmental Biology

Background:

  • Model organisms are crucial for biological research.
  • They allow the study of specific biological problems.

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  • Discoveries made using model organisms can be applied to other species.