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First Description of Hypertrophic Cardiomyopathy Phenotype in Apparently Healthy Cats in Morocco: An
Hanaa El Atmani1, Faouzi Kichou2, Alberto Tarducci3
1Unit of Equines and Small Animals, Department of Medicine, Surgery and Reproduction, Hassan II Agronomic and Veterinary Institute, Rabat BP 6202, Morocco.
Insights
Subclinical Hypertrophic Cardiomyopathy Phenotype (HCM-Ph) affects nearly 10% of apparently healthy cats in Morocco. This common heart disorder in cats can lead to fatal outcomes, emphasizing the need for veterinary awareness.
Area of Science:
- Veterinary Cardiology
- Feline Medicine
- Cardiovascular Research
Background:
- Hypertrophic Cardiomyopathy Phenotype (HCM-Ph) is a prevalent myocardial disorder in cats globally.
- Existing research indicates prevalence rates between 8% and 34%, but data from Morocco was lacking.
Purpose of the Study:
- To determine the prevalence of HCM-Ph in apparently healthy cats in Morocco.
- To describe epidemiological and echocardiographic features of affected cats.
- To compare feline patients in the ACVIM stages B1 and B2.
Main Methods:
- Echocardiographic screening of 81 apparently healthy cats.
- Data collection on epidemiological factors and echocardiographic measurements.
- Comparison of cats classified into ACVIM stages B1 and B2.
Main Results:
- The overall prevalence of HCM-Ph was 9.88% in the studied cat population.
- Affected cats were typically young (median age 4 years) with a male predominance (75%).
- Echocardiographic findings included left ventricular hypertrophy, normal ventricular diameters, preserved function, and variable left atrial enlargement. Stage B2 cats were older and had greater hypertrophy than stage B1 cats.
Conclusions:
- Subclinical HCM-Ph is common in apparently healthy Moroccan cats.
- Veterinarians must recognize HCM-Ph's clinical significance due to potential fatal cardiovascular events.
- Myocardial hypertrophy and age may play roles in clinical staging and risk assessment for HCM-Ph.
Abstract:
Hypertrophic Cardiomyopathy Phenotype (HCM-Ph) is the most common group of myocardial disorders in cats. It has been the subject of research worldwide with prevalence rates ranging from 8% to 34%. However, there is no data available on its occurrence in Morocco. This study aimed to investigate the prevalence of HCM-Ph in apparently healthy cats in Morocco, describe the epidemiological and echocardiographic findings of affected cats and to compare patients in ACVIM stages B1 and B2. A total of 81 apparently healthy cats underwent echocardiographic screening. The overall prevalence of HCM-Ph was 9.88% (95% CI: 4.36-18.54%). The median age was four years (IQR 3.5-5.5) and a male overrepresentation (75%) was noted. Affected cats exhibited various echocardiographic patterns of left ventricular hypertrophy, normal left ventricular diameters, preserved fractional shortening and different degrees of left atrial enlargement. Cats in B2 stage were older and had more myocardial hypertrophy compared to cats in B1 stage, highlighting the potential role of wall thickness in clinical staging and risk assessment. Subclinical HCM-Ph is relatively common in apparently healthy cats in Morocco. Veterinarians should be aware of its clinical importance, as despite the fact that it presents no clinical signs, it can have fatal cardiovascular outcomes.
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