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Updated: Jun 27, 2026

Loop-mediated Isothermal Amplification (LAMP) Assays for the Species-specific Detection of Eimeria that Infect Chickens
06:57

Loop-mediated Isothermal Amplification (LAMP) Assays for the Species-specific Detection of Eimeria that Infect Chickens

Published on: February 20, 2015

Prevalence and Epidemiological Characteristics of Mycoplasma synoviae Infection in Chickens in Mainland China

Xinyuan Liu1,2, Huiling Zhang3, Zihan Huang1,2

  • 1Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.

Animals : an Open Access Journal From MDPI
|June 26, 2026
PubMed

Insights

Mycoplasma synoviae (MS) is widespread in Chinese chickens, with high serological but moderate molecular prevalence. Breeder flocks show higher infection rates, indicating a need for better surveillance and control strategies.

Area of Science:

  • Veterinary Epidemiology
  • Avian Pathology
  • Infectious Disease Surveillance

Background:

  • Mycoplasma synoviae (MS) presents a significant, ongoing challenge to the poultry industry in China.
  • A comprehensive, nationwide assessment of MS prevalence and epidemiology is currently lacking.

Purpose of the Study:

  • To systematically review and meta-analyze existing studies to quantify the pooled prevalence of MS in China.
  • To evaluate key epidemiological characteristics and identify sources of heterogeneity in MS prevalence.
  • To assess diagnostic disparities between serological and molecular detection methods.

Main Methods:

  • Systematic literature search across multiple databases for peer-reviewed studies on MS in China.
  • Application of random-effects models for estimating and comparing pooled seroprevalence and molecular detection prevalence.
  • Subgroup analyses to explore heterogeneity based on geographical region, production type, and age groups.

Main Results:

  • A high serological prevalence contrasted with a moderate molecular detection prevalence, suggesting widespread past exposure, chronic carriage, or vaccination.
  • Northwest China reported the highest seroprevalence (61.8%), though inter-regional differences were not significant.
  • Breeder flocks showed a relatively high pooled prevalence (69.6%), with potential epidemiological significance.

Conclusions:

  • Mycoplasma synoviae is widely distributed across chickens in mainland China.
  • The discrepancy between serological and molecular results complicates prevalence interpretation.
  • Further research with standardized surveillance and vaccination data is crucial for effective MS control.
Keywords:
Mycoplasma synoviaeage groupsbreedersmainland Chinameta-analysismolecular detection prevalenceseroprevalence

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