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Related Concept Videos

Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

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Related Experiment Video

Updated: Jun 27, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
06:51

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

Fatal Systemic Infection Caused by Multidrug-Resistant Clostridioides difficile in a Domestic Rabbit: A Comprehensive

Vlad Iorgoni1, Livia Stanga2, Paula Nistor1

  • 1Department of Infectious Diseases and Preventive Medicine, Faculty of Veterinary Medicine, University of Life Sciences "King Mihai I" from Timişoara, 300645 Timişoara, Romania.

Antibiotics (Basel, Switzerland)
|June 26, 2026
PubMed
Summary
This summary is machine-generated.

A fatal case of Clostridioides difficile infection in a farmed rabbit highlights the risks of antimicrobial-induced dysbiosis. Prudent antibiotic use and monitoring are crucial for preventing severe disease and potential public health risks.

Area of Science:

  • Veterinary Medicine
  • Microbiology
  • Animal Health

Background:

Keywords:
Clostridioides difficileantimicrobial resistanceenterocolitisgastrointestinal infectionrabbittoxigenic strains

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  • Rabbit farming faces challenges from enteric diseases, with Clostridioides difficile (C. difficile) emerging as a significant pathogen.
  • C. difficile infections in rabbits can lead to systemic dissemination and pose public health concerns.
  • Previous studies have indicated the potential for C. difficile to affect farmed rabbit populations.