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Updated: Jun 27, 2026

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research

Published on: October 27, 2023

Antibiotic Prescribing Patterns for Pulpitis in Pediatric Dentistry: A Systematic Review and Meta-Analysis.

Carmen Machuca-Portillo¹, Cira Suárez-Marchena¹, Lucy Chandler-Gutiérrez¹

¹Department of Stomatology, Pediatric Dentistry Division, School of Dentistry, University of Sevilla, C/Avicena s/n, 41009 Sevilla, Spain.

Antibiotics (Basel, Switzerland)

|June 26, 2026

Summary

Pediatric dentists sometimes overprescribe antibiotics for pulpitis, a dental condition treatable with local procedures. This review found a 14% pooled prevalence of antibiotic use, highlighting a gap in antimicrobial stewardship for children.

Keywords:

antibiotic prescribing antimicrobial stewardship clinical guidelines pediatric dentistry pulpitis

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Last Updated: Jun 27, 2026

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research

Published on: October 27, 2023

Area of Science:

Pediatric Dentistry
Pharmacology
Infectious Diseases

Background:

Pulpitis is a common pediatric dental issue, typically managed with local treatment.
Antibiotics are often overprescribed for pulpitis, contributing to antimicrobial resistance.
Misuse of antibiotics in dentistry poses risks to public health.

Purpose of the Study:

To evaluate antibiotic prescribing patterns for pulpitis in pediatric patients.
To assess adherence to current clinical guidelines for pulpitis management.
To identify areas for improved antimicrobial stewardship in pediatric dental practice.

Main Methods:

Systematic review following PRISMA 2020 guidelines.
Searched PubMed/MEDLINE, Scopus, and Embase for observational studies.
Conducted a meta-analysis of proportions and assessed risk of bias and certainty of evidence.

Main Results:

Five studies included, with antibiotic prescribing rates for pulpitis from 0.6% to 50.0%.
Pooled prevalence of antibiotic prescribing was 14.0%, with significant heterogeneity.
Amoxicillin and amoxicillin-clavulanic acid were most common; clindamycin for penicillin allergy.

Conclusions:

Inappropriate antibiotic use for pulpitis persists in pediatric dentistry.
A gap exists between evidence-based guidelines and clinical practice.
Targeted antimicrobial stewardship strategies are needed to optimize antibiotic use.