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Related Experiment Video

Updated: Jun 27, 2026

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
04:08

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions

Published on: April 28, 2026

Innovations in Advanced Endoscopic Resection of Early Upper Gastrointestinal Cancer.

Andrea Sorge1,2, Pieter Jan Poortmans3,4,5, Michele Montori6

  • 1Department of Surgery, Oncology and Gastroenterology, University of Padua, 35128 Padua, Italy.

Journal of Clinical Medicine
|June 26, 2026
PubMed
Summary

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Endoscopic resection (ER) advances offer safer, organ-preserving treatment for early upper gastrointestinal cancers. Innovations in imaging, tools, and techniques enhance precision and expand therapeutic options for complex lesions.

Area of Science:

  • Gastroenterology
  • Endoscopic Surgery
  • Oncology

Background:

  • Endoscopic resection (ER) is preferred for early upper GI cancers due to safety over surgery.
  • Technological advancements have significantly improved endoscopic submucosal dissection (ESD) scope, safety, and precision.
  • This review focuses on key innovations in upper GI ESD practice.

Purpose of the Study:

  • To synthesize current evidence on advances in upper gastrointestinal endoscopic submucosal dissection (ESD).
  • To highlight innovations enhancing lesion detection, characterization, and intraoperative visualization.
  • To discuss new resection strategies, closure technologies, and deep resection techniques.

Main Methods:

  • Review of current evidence on technological and procedural innovations in upper GI ESD.
Keywords:
REACTSTERartificial intelligenceendoscopic full-thickness resectionendoscopic resection of gastric cancerendoscopic submucosal dissectionintermuscular dissectionnon-curative resectionoesophageal cancertherapeutic endoscopetraction

Related Experiment Videos

Last Updated: Jun 27, 2026

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
04:08

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions

Published on: April 28, 2026

  • Analysis of enhanced imaging modalities and new-generation therapeutic endoscopes.
  • Evaluation of novel resection strategies, closure technologies, and deep resection techniques.

    • Main Results:

    • Enhanced imaging and new endoscopes improve lesion detection and procedural capability.
    • Novel resection strategies and closure technologies simplify procedures and reduce morbidity.
    • Deep resection techniques enable organ preservation for invasive cancers and subepithelial lesions.
    • Risk stratification and AI-driven training enhance management and standardize technique acquisition.

    Conclusions:

    • Innovations are transforming upper GI oncology, establishing minimally invasive endoscopy as a primary therapeutic strategy.
    • Advances in ESD are expanding organ-preserving options for a wider range of gastrointestinal malignancies.
    • Future directions include refining non-curative resection management and leveraging AI for training and procedural support.