Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 27, 2026

A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging
05:51

A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging

Published on: March 17, 2023

Aggregation-Induced Emission (AIE) Probe-Labeled Nanotheranostics: A Mini-Review.

Yilin Ma1, Yingying Li2, Chuanbin Wu3

  • 1International School, Jinan University, Guangzhou 510632, China.

Pharmaceuticals (Basel, Switzerland)
|June 26, 2026
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cuproptosis-Related Genes in Immune Infiltration and Diagnosis in Hepatitis B Virus-Related Acute Liver Failure.

Exploration (Beijing, China)·2026
Same author

Microneedle technology integrated with diverse therapeutic modalities for hair regrowth in alopecia.

Acta pharmaceutica Sinica. B·2026
Same author

Toward an AI Era: Application of Artificial Intelligence in Inclusion Complex Screening.

Pharmaceutics·2026
Same author

Light-driven thermotropic hydrogel with nanomodulator enables lipid intervention and cavity delivery for postsurgical tumor therapy.

Cell reports. Medicine·2026
Same author

Dual-responsive ionic liquid based foam-to-gel for precision vaginal delivery of progesterone.

Acta biomaterialia·2026
Same author

The Application of Machine Learning in the Development of Co-Amorphous Dry Powder Inhalation.

AAPS PharmSciTech·2026
Same journal

Correction: Jiménez-Sánchez et al. Antioxidant Enzymes Genetic Variants Associated with Urticaria/Angioedema Induced by Cross-Reactive Hypersensitivity to Nonsteroidal Anti-Inflammatory Drugs. <i>Pharmaceuticals</i> 2026, <i>19</i>, 522.

Pharmaceuticals (Basel, Switzerland)·2026
Same journal

Correction: Zhao et al. Multifunctional Gel Films of Marine Polysaccharides Cross-Linked with Poly-Metal Ions for Wound Healing. <i>Pharmaceuticals</i> 2022, <i>15</i>, 750.

Pharmaceuticals (Basel, Switzerland)·2026
Same journal

Intravenous Immunoglobulin Reveals a Novel Protective Mechanism: Targeting the GBP5-Driven Pyroptosis Axis in Experimental Colitis.

Pharmaceuticals (Basel, Switzerland)·2026
Same journal

Icariin Attenuates Renal Injury in Streptozotocin-Induced Diabetic Rats with and Without Adenine-Induced Chronic Kidney Disease.

Pharmaceuticals (Basel, Switzerland)·2026
Same journal

AI-Assisted Identification of a Putative Allosteric Ligand Targeting the CDK4/Cyclin D1 Protein-Protein Interface.

Pharmaceuticals (Basel, Switzerland)·2026
Same journal

Development and Study of Hydrophilic Ointment Compositions with a Dextrin/Polyvinyl Alcohol/Iodine Complex (D/PVA/I).

Pharmaceuticals (Basel, Switzerland)·2026
See all related articles
This summary is machine-generated.

Aggregation-induced emission (AIE) agents overcome limitations of traditional fluorescent probes in nanotheranostics. This review explores AIE nanoprobes for precision medicine applications, addressing challenges for clinical translation.

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Nanotechnology

Background:

  • Nanotheranostics combine diagnosis and therapy on nanoscale platforms for precision medicine.
  • Traditional fluorescent probes suffer from aggregation-caused quenching (ACQ), limiting imaging.
  • Aggregation-induced emission (AIE) agents enhance fluorescence upon aggregation, solving ACQ issues.

Purpose of the Study:

  • To systematically review nanotheranostic systems utilizing AIE agents.
  • To discuss AIE probe design strategies and disease-specific applications.
  • To analyze challenges and future directions for AIE nanotheranostics in clinical practice.

Main Methods:

  • Review of literature on AIE mechanisms and nanotheranostic applications.
  • Categorization of AIE nanoprobes based on nanocarrier types (liposomes, polymer nanoparticles, self-assembling systems).
Keywords:
AIEgensaggregation induced emission (AIE)bioimagingcancer theranosticsdrug deliverynanotheranostics

More Related Videos

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
07:54

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

Published on: March 25, 2019

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy
12:58

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy

Published on: September 12, 2019

Related Experiment Videos

Last Updated: Jun 27, 2026

A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging
05:51

A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging

Published on: March 17, 2023

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
07:54

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

Published on: March 25, 2019

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy
12:58

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy

Published on: September 12, 2019

  • Emphasis on disease-specific AIE nanotheranostic designs for tumors, neurodegenerative, and inflammatory diseases.

    • Main Results:

    • AIE agents provide a superior alternative to traditional fluorescent probes due to their unique emission properties.
    • Diverse nanocarrier strategies enable effective loading and function of AIE probes.
    • Tailored AIE nanotheranostics show promise for specific pathological microenvironments.

    Conclusions:

    • AIE nanotheranostics offer significant advantages for advanced imaging and therapy in precision medicine.
    • Overcoming challenges in clinical translation is crucial for realizing the full potential of AIE nanomedicine.
    • Future developments in AIE nanotheranostics will drive personalized medicine approaches.