Related Experiment Video
Updated: Jun 27, 2026

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts
Published on: July 18, 2025
A Robust Current-Feedback Operational Amplifier-Based Front-End Amplifier for Electrocardiogram Signal Noise Removal
Suchada Sitjongsataporn1, Panavy Pookaiyaudom1, Phimchanok Sakunpongpitiporn2
1Department of Electronic Engineering, School of Electrical and Electronic Engineering (SEE), Mahanakorn University of Technology, Nongchok, Bangkok 10530, Thailand.
This study presents a novel electrocardiogram (ECG) amplifier that effectively removes noise like baseline wander and powerline interference. The circuit enhances ECG signal clarity for improved wearable monitoring.
Area of Science:
- Biomedical Engineering
- Electronics Engineering
Background:
- Electrocardiogram (ECG) signals are crucial for cardiac monitoring but are susceptible to various noise sources.
- Common ECG noise includes baseline wander (BW), powerline interference (PLI), and motion artifacts, which can obscure vital diagnostic information.
Purpose of the Study:
- To develop and validate a novel front-end amplifier circuit for ECG noise removal.
- To enhance the fidelity of ECG signals for improved diagnostic accuracy, particularly in wearable applications.
Main Methods:
- Design of a current-feedback operational amplifier (CFOA)-based ECG pre-amplifier utilizing the AD844 operational amplifier.
- Implementation of a balancing instrumentation amplifier architecture for superior noise rejection.
- Integration of a novel cascaded low-pass filter (LPF) stage for effective high-frequency interference suppression.
Main Results:
- The proposed CFOA-based amplifier achieved a high common-mode rejection ratio (CMRR) of 75.4 dB.
- A mid-band gain of 46.5 dB was obtained, demonstrating effective signal amplification.
- The circuit successfully eliminated baseline wander (BW) and powerline interference (PLI).
Conclusions:
- The developed ECG noise removal front-end amplifier demonstrates robust performance suitable for high-fidelity wearable ECG monitoring.
- The innovative architecture and filtering stages effectively denoise ECG signals, improving diagnostic signal quality.
Related Concept Videos
Instrumentation Amplifier
To overcome this challenge, an ECG machine utilizes an instrumentation amplifier. This specialized amplifier is...
Inverting and Non-inverting OpAmps
Characteristics of OpAmp
Operational Amplifiers
Cascaded Op Amps
In a cascaded system, each op-amp is referred to as a stage. The output of one stage drives the input of the subsequent stage. As the input signal passes through...
Design Example: Vintage Mixing Console
The specifications for the pre-amplifier were clear. It needed to amplify the audio signal by a factor of 10, have an input impedance above 10...
