Tjap1/Pilt Is a cis-Golgi-Associated Protein Required for Golgi Integrity and Normal Drug Transporter Expression in

Junqiao Mi1,2, Annabelle Schoder1, Aili Sun1

  • 1Department of Anesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Würzburg, 97080 Würzburg, Germany.

Pharmaceutics
|June 26, 2026
PubMed
Summary

Tight junction-associated protein 1 (Tjap1) is crucial for Golgi structure in brain microvascular endothelial cells (BMECs). Its absence causes Golgi fragmentation and alters blood-brain barrier (BBB) transporter expression, impacting drug transport.

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