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Updated: Jun 27, 2026

In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines
05:32

In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines

Published on: May 12, 2023

Heteroaromatic Pyrazole-Based Carbohydrazones: Structure-Dependent Redox Activity, DNA-Associated Spectroscopic

Aliye Gediz Erturk1, Ertuğrul Yiğit1

  • 1Department of Chemistry, Faculty of Science & Arts, Ordu University, 52200 Ordu, Turkey.

Molecules (Basel, Switzerland)
|June 26, 2026
PubMed
Summary

Novel pyrazole carbohydrazones with diverse heteroaromatic groups show promising antioxidant, photoprotective, and selective cytotoxic activities. Compound 3f exhibits strong antioxidant and photoprotective effects, while 3e excels in iron chelation, highlighting tunable bioactivity.

Keywords:
A431 epidermoid carcinoma cellsCT-DNA-associated spectroscopic responseantioxidant activitycytotoxicityheteroaromatic substitutionphotoprotective activitypyrazole-based carbohydrazonesstructure–activity relationship

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