Positive-Strand RNA Viral RdRps: From Structure Conservation and Activity Assay to Drug Development

Siyuan Zhao1, Ziyu Lin1, Minglian Wang1

  • 1College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.

Abstract

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Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
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