Related Experiment Video
Updated: Jun 27, 2026

Combining Analysis of DNA in a Crude Virion Extraction with the Analysis of RNA from Infected Leaves to Discover New Virus Genomes
Published on: July 27, 2018
Genetic Evolutionary Analysis and Characterization of Bovine Viral Diarrhea Virus in Gansu Province, China
Cong Li1,2, Shandian Gao2, Yongli Mo2
1College of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
Abstract:
This study aimed to investigate the current epidemiology and genetic evolution of bovine viral diarrhea virus (BVDV) on cattle farms in Gansu Province, China, between 2021 and 2025. A total of 749 samples from 62 farms across 14 cities and prefectures in Gansu were tested. The overall BVDV positivity rate was 19.89%, determined by amplification of the 5'-UTR and Npro regions. Seven subtypes were identified: BVDV-1a, -1b, -1d, -1m, -1v, -1u, and -2a. BVDV-1u was the predominant subtype (59.06%), followed by BVDV-1v (13.42%). The greatest subtype diversity was observed in Jinchang City and Gannan Tibetan Autonomous Prefecture. A non-cytopathic BVDV-1v strain, designated YC-2025-Gansu2 (GenBank accession no. PV945812.1), was isolated. This study expands the BVDV subtype database for Gansu and supports the development of subtype-specific prevention strategies in the region.
Related Concept Videos
Single Nucleotide Polymorphisms-SNPs
Viral Mutations
Bacterial Gastroenteritis

