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Updated: Jun 27, 2026
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Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases
Published on: January 1, 2016
Quorum Sensing Modulators as Antibiotic Alternatives in Animal Production: From Bacterial Signaling to Gut Health and
Chenxin Tang1, Kehui Ouyang1, Mingren Qu1
1Jiangxi Province Key Laboratory of Animal Nutrition and Feed, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Veterinary Sciences
|June 26, 2026
Summary
Quorum sensing (QS) modulators offer sustainable solutions for intensive animal production by reducing antibiotic use and environmental impact. This review explores QS modulators from various sources, addressing challenges and future directions for antibiotic-free farming.
Area of Science:
- Agricultural Science
- Microbiology
- Environmental Science
Background:
- Overuse of antibiotics in animal production drives antimicrobial resistance and pollution.
- Gut dysbiosis and disease outbreaks hinder sustainable development in intensive farming.
- Quorum sensing (QS) regulates bacterial communication and community functions.
Purpose of the Study:
- To review quorum sensing (QS) modulators as alternatives to antibiotics in animal production.
- To explore sources, advantages, and challenges of QS modulators.
- To provide a basis for translating QS regulation into sustainable farming practices.
Main Methods:
- Literature review of QS modulators from plants, microorganisms, animals, and synthetic origins.
- Analysis of QS modulator advantages, including environmental benignity and target specificity.
- Identification of challenges: environmental interference, resistance, cost, and biosafety.
Main Results:
- QS modulators offer a promising strategy to decrease antibiotic reliance and environmental emissions.
- Diverse sources of QS modulators exist, each with unique properties.
- Key challenges impede widespread adoption, requiring further research and development.
Conclusions:
- QS modulators present innovative strategies for sustainable animal production and antibiotic-free husbandry.
- Future research must focus on enhancing specificity, stability, affordability, and safety.
- Translating QS-regulation technologies to farm-level applications requires addressing current limitations.
Keywords:
animal feedenvironmental sustainabilitygut microbiotaintestinal homeostasisproduction efficiencyquorum sensingstress alleviationMore Related Videos
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