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Updated: Jun 27, 2026
05:25
Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
Published on: August 14, 2019
Longitudinal Changes in Overactive Bladder Symptoms After Prostatic Urethral Lift for Benign Prostatic Hyperplasia: A
Go Anan1, Kanya Kaga2, Yosuke Fujishima3
1Department of Urology, Yotsuya Medical Cube, Tokyo, Japan.
Summary
Prostatic urethral lift (PUL) significantly improves overactive bladder (OAB) symptoms in men with benign prostatic hyperplasia (BPH). About half of patients with OAB experienced meaningful symptom relief within six months after the PUL procedure.
Area of Science:
- Urology
- Men's Health
- Lower Urinary Tract Symptoms
Background:
- Benign prostatic hyperplasia (BPH) frequently coexists with overactive bladder (OAB) symptoms.
- The effectiveness of prostatic urethral lift (PUL) for OAB symptoms in BPH patients requires further clarification.
Purpose of the Study:
- To assess the longitudinal impact of PUL on OAB symptoms, measured by the OAB symptom score (OABSS).
- To identify predictors of clinically meaningful improvement in OAB symptoms following PUL.
Main Methods:
- A prospective, single-center study involving 140 men undergoing PUL.
- Assessment of OABSS, IPSS, QOL, and uroflowmetry at baseline and 1, 3, and 6 months post-procedure.
- OAB defined by urgency (OABSS Q3 ≥ 2) and total OABSS ≥ 3; meaningful improvement defined as ≥ 3-point OABSS reduction.
Main Results:
- PUL demonstrated significant improvements in IPSS, QOL, Qmax, and PVR post-procedure.
- Total OABSS significantly decreased from 5.8 at baseline to 3.7 at 6 months (p < 0.001).
- Clinically meaningful improvement in OABSS was achieved by 57.8% of patients with preoperative OAB at 6 months; higher baseline OABSS predicted better response.
Conclusions:
- PUL provides significant and sustained improvement in storage symptoms for up to 6 months.
- Approximately half of men with pre-existing OAB achieve meaningful symptom relief after PUL.
- PUL is an effective treatment option for men with BPH and coexisting OAB symptoms.
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