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Updated: Jun 27, 2026
04:30
An Experimental Paradigm for Measuring the Effects of Ageing on Sentence Processing
Published on: October 25, 2019
The Effect of Age on Post-Stroke Language Outcomes
Sophie M Roberts1, Rachel M Bruce1, Thomas M H Hope1
1Department of Imaging Neuroscience, University College London, London, UK, ucl.ac.uk.
Journal of Aging Research
|June 26, 2026
Summary
Older age at stroke onset worsens post-stroke language abilities, especially with larger lesions and initial severity. Age does not hinder language recovery, but assessment interpretation should consider age for accuracy.
Area of Science:
- Neurology
- Psycholinguistics
- Gerontology
Background:
- Chronological age is a factor in stroke recovery.
- Understanding age-related language deficits post-stroke is crucial.
Purpose of the Study:
- Investigate the impact of chronological age at stroke onset on language abilities and recovery.
- Identify language tasks sensitive to age.
- Examine if age effects are modified by lesion size, initial severity, or education.
- Determine if age influences aphasia recovery.
Main Methods:
- Assessed language abilities in 749 participants using the Comprehensive Aphasia Test (CAT) and self-reported measures.
- Utilized multiple linear regression to analyze CAT scores and self-reported recovery at 1 year post-stroke.
- Controlled for lesion size, initial severity, sex, handedness, education, and time post-stroke.
Main Results:
- Older age at stroke onset correlated with poorer performance in multiple language domains (e.g., repetition, fluency, naming, comprehension).
- Age-related disadvantages were amplified in individuals with larger lesions and more severe initial aphasia.
- No evidence indicated that older age hindered language recovery across subgroups.
Conclusions:
- Older age at stroke onset significantly impacts post-stroke language outcomes.
- Aphasia assessments are sensitive to age-related differences.
- Age should be considered in interpreting assessment scores for optimized diagnosis and prognosis.
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