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Related Experiment Video

Updated: Jun 27, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Aggressive Central Giant Cell Granuloma: A Case Report.

R Hariharan1, Devotta F Andrew1, G Satheesh1

  • 1Oral and Maxillofacial Surgery, Adhiparasakthi Dental College and Hospital, Melmaruvathur, IND.

Cureus
|June 26, 2026
PubMed
Summary
This summary is machine-generated.

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Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...

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Central giant cell granuloma (CGCG) is a rare jaw lesion. This case highlights an aggressive variant in the maxilla, successfully treated with surgery and cryotherapy, with minor follow-up changes.

Area of Science:

  • Oral and Maxillofacial Surgery
  • Pathology
  • Radiology

Background:

  • Central giant cell granuloma (CGCG) is an uncommon, benign intraosseous jaw lesion.
  • Aggressive CGCG can cause rapid growth, expansion, pain, root resorption, and recurrence.
  • Typical presentation involves the anterior mandible in young females.
Keywords:
benign tumorscentral giant cell granulomagiant cell tumorjaw lesionmaxillary tumor

Related Experiment Videos

Last Updated: Jun 27, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019