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Related Experiment Video

Updated: Jun 27, 2026

Evaluation of the Storage Stability of Extracellular Vesicles

Evaluation of the Storage Stability of Extracellular Vesicles

Published on: May 22, 2019

Extracellular Vesicles in Wearable Delivery Systems for Cosmeceutical Applications.

Tiantai Wen^1,2, Yifan Gu^1,2, Guozhen Liu^1,2

¹Integrated Devices and Intelligent Diagnosis (ID2) Laboratory, CUHKSZ-Boyalife Regenerative Medicine Engineering Joint Laboratory, School of Medicine, The Chinese University of Hong Kong, Shenzhen, China.

Advanced Healthcare Materials

|June 26, 2026

Summary

This summary is machine-generated.

Wearable devices offer advanced delivery for extracellular vesicles (EVs) in skincare, improving skin penetration and sustained release. These systems address limitations of traditional methods for cosmetic and dermatological applications.

Keywords:

clinical efficacy of EVs cosmeceuticals extracellular vesicles topical EVs delivery transdermal EVs application wearable devices

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Evaluation of the Storage Stability of Extracellular Vesicles

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Characterizing Extracellular Vesicles from Biological Fluids

Characterizing Extracellular Vesicles from Biological Fluids

Published on: February 28, 2025

Area of Science:

Cosmeceuticals and Dermatology
Biomaterials and Nanotechnology

Background:

Extracellular vesicles (EVs) show promise for skin regeneration, anti-inflammatory effects, and repair.
Conventional topical and injectable delivery of EVs face challenges like poor skin penetration, instability, and variable bioavailability.

Purpose of the Study:

To review recent advances in wearable-assisted delivery systems for extracellular vesicles (EVs) in cosmetic and dermatological applications.
To highlight transdermal delivery, sustained release, and personalized skin monitoring strategies using wearable platforms.

Main Methods:

Review of wearable platforms including microneedle patches, hydrogels, iontophoretic devices, and stimuli-responsive systems for EV delivery.
Discussion of different EV sources and wearable formats, considering formulation and translational aspects.

Main Results:

Wearable platforms can potentially enhance EV retention, transdermal transport, and localized delivery compared to conventional topical formulations.
Various wearable formats offer distinct advantages for EV delivery in skincare.

Conclusions:

Wearable-assisted EV delivery systems represent a promising advancement for cosmetic and dermatological applications.
Challenges in EV stability, scalable production, regulation, and safety need to be addressed for clinical translation.
Future developments in biomaterials and wearable technology could enable personalized, EV-based skincare solutions.