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Related Experiment Video

Updated: Jun 28, 2026

Automated 90Sr Separation and Preconcentration in a Lab-on-Valve System at Ppq Level
08:53

Automated 90Sr Separation and Preconcentration in a Lab-on-Valve System at Ppq Level

Published on: June 6, 2018

Direct measurement method for 90Y activity in urine.

Yan Ma1,2, Lina Ma1,2, Hui Zhang1,2

  • 1China Institute for Radiation Protection, 102 Xuefu Street, Taiyuan City 030006, Shanxi Province, People's Republic of China. mayan@cirp.org.cn.

Analytical Methods : Advancing Methods and Applications
|June 26, 2026
PubMed
Summary
This summary is machine-generated.

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Accurate measurement of Yttrium-90 (90Y) in urine is vital for radiation safety after radioembolization. Both liquid scintillation counting and Cherenkov counting methods offer reliable accuracy for determining 90Y activity in urine samples.

Area of Science:

  • Nuclear medicine
  • Radiochemistry
  • Radiation safety

Background:

  • Yttrium-90 (90Y) radioembolization treats unresectable hepatocellular carcinoma.
  • Accurate monitoring of 90Y excretion in urine is essential for radiation safety.
  • Urine analysis for 90Y activity requires sensitive and precise detection methods.

Purpose of the Study:

  • To evaluate the feasibility of direct Yttrium-90 (90Y) activity determination in urine.
  • To compare the performance of liquid scintillation counting (LSC) and Cherenkov counting methods.
  • To investigate the impact of urine optical properties on counting efficiency and accuracy.

Main Methods:

  • Comparison of liquid scintillation counting (LSC) and Cherenkov counting for 90Y detection in urine.

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Biochemical Measurement of Neonatal Hypoxia
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Published on: August 24, 2011

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Last Updated: Jun 28, 2026

Automated 90Sr Separation and Preconcentration in a Lab-on-Valve System at Ppq Level
08:53

Automated 90Sr Separation and Preconcentration in a Lab-on-Valve System at Ppq Level

Published on: June 6, 2018

Biochemical Measurement of Neonatal Hypoxia
13:13

Biochemical Measurement of Neonatal Hypoxia

Published on: August 24, 2011

  • Analysis of counting efficiency, background counts, and minimum detectable activity (MDA).
  • Assessment of method accuracy using spiked urine samples with known 90Y concentrations.

    • Main Results:

    • Counting efficiency for both LSC and Cherenkov counting positively correlated with urine light transmittance.
    • LSC showed higher counting efficiency under similar light transmittance conditions.
    • Cherenkov counting demonstrated lower background counts and MDA, performing better with high light transmittance.

    Conclusions:

    • Both LSC and Cherenkov counting provide reliable accuracy for 90Y determination in urine.
    • Cherenkov counting offers advantages in sensitivity (lower MDA) under specific conditions.
    • This study supports the reliable detection of 90Y in urine for radiation safety assessments.