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Updated: Jun 28, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
[Neuropsychological disorders in patients with serofast state]
U S Kostina1,2, V V Shprakh1, N A Shpakova2
1Irkutsk State Institute for Advanced Training of Doctors - a branch of the Russian Medical Academy of Continuing Professional Education, Irkutsk, Russia.
None:
This study involved an analysis of neuropsychological functions in 68 patients, aged 27 to 64 years, who exhibited serofast state following syphilitic infection. A comprehensive approach was adopted, including questionnaires, neurological examinations, and cognitive assessments to evaluate participants' cognitive status. The primary objective of this research was to assess cognitive functioning among individuals in this population. The results indicated that a significant proportion of the subjects displayed a persistent craving for alcohol, suggesting potential dependence and alterations in their psycho-emotional state. Notably, among male participants, there was a higher incidence of aggressive behavior, difficulties in social adaptation, and a tendency toward spontaneous, unpredictable actions. Moreover, there was frequent disregard for generally accepted norms and behavioral standards. Conversely, female participants were more likely to exhibit abrupt mood fluctuations, which often resulted in conflictual behavior characterized by aggressive elements. Additionally, there were manifestations of vindictiveness and suspicion among the subjects. The inclination to manage emotional states through alcohol consumption was particularly evident among the women involved in the study.
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