Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lipoprotein(a) plasma levels and coagulation biomarkers: Results from a comprehensive laboratory assessment in an angiographically controlled cardiovascular cohort.

Journal of clinical lipidology·2026
Same author

Autonomic effects and ablation success after pulsed field and cryoballoon ablation - A SINGLE SHOT CHAMPION substudy.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2026
Same author

Standardized processing of explanted hearts after stereotactic arrhythmia radiotherapy (Bio-STAR): a STOPSTORM framework and first human findings.

European heart journal open·2026
Same author

When the Pacemaker Goes Rogue: Pacemaker-Induced Tachycardia, Syncope, and Car Crash.

Case reports in cardiology·2026
Same author

Semaglutide-associated Twiddler syndrome.

JCEM case reports·2026
Same author

Stereotactic arrhythmia radioablation for refractory ventricular tachycardia: the STOPSTORM.eu study.

European heart journal·2026
Same journal

Early Safety Profile Using Pulsed Field Ablation: Prospective Multicenter DISRUPT-AF Study.

JACC. Clinical electrophysiology·2026
Same journal

Leveraging Large Language Models to Identify In-Hospital Cardiac Arrest.

JACC. Clinical electrophysiology·2026
Same journal

Repolarization and Activation Mapping in Ventricular Tachycardia Ablation: The REDEEM Study.

JACC. Clinical electrophysiology·2026
Same journal

Physiological Markers of Effective Autonomic Denervation Are Associated With Outcomes After Cardioneuroablation for Vasovagal Syncope.

JACC. Clinical electrophysiology·2026
Same journal

Atrial Cardiomyopathy and Atrial Fibrillation in Endurance Athletes: Differentiating Physiological Adaptation From Pathological Remodeling.

JACC. Clinical electrophysiology·2026
Same journal

Measure Twice, Ablate Once: When Discretion Proved the Better Part of Valor for Varipulse.

JACC. Clinical electrophysiology·2026
See all related articles
  1. Home
  3. Pvi Durability After Pfa Or Rfa In Persistent-af: Insights From A Mandated Prospective Remapping Study.
  1. Home
  3. Pvi Durability After Pfa Or Rfa In Persistent-af: Insights From A Mandated Prospective Remapping Study.

Related Experiment Video

Robotic Ablation of Atrial Fibrillation
11:21

Robotic Ablation of Atrial Fibrillation

Published on: May 29, 2015

PVI Durability After PFA or RFA in Persistent-AF: Insights From a Mandated Prospective Remapping Study.

Oskar M Galuszka1, Thomas Kueffer1, Samuel H Baldinger1

  • 1Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

JACC. Clinical Electrophysiology
|June 26, 2026

View abstract on PubMed

Summary
This summary is machine-generated.

Pulsed field ablation (PFA) shows durable pulmonary vein isolation (PVI) comparable to radiofrequency ablation (RFA) in persistent atrial fibrillation (AF). Recurrence rates were similar, indicating non-PV mechanisms may drive AF after PVI.

Keywords:
persistent atrial fibrillationpulmonary vein isolationpulsed-field ablationradiofrequency ablationremapping study

More Related Videos

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
10:39

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding

Published on: August 30, 2024

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
10:17

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

Related Experiment Videos

Robotic Ablation of Atrial Fibrillation
11:21

Robotic Ablation of Atrial Fibrillation

Published on: May 29, 2015

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
10:39

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding

Published on: August 30, 2024

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
10:17

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Pulmonary vein isolation (PVI) is crucial for atrial fibrillation (AF) ablation.
  • Reconnections and non-pulmonary vein (PV) mechanisms contribute to persistent AF recurrence after ablation.

Purpose of the Study:

  • To compare the durability of PVI and arrhythmia recurrence rates between pulsed field ablation (PFA) and radiofrequency ablation (RFA) in patients with persistent AF.

Main Methods:

  • Prospective enrollment of persistent AF patients undergoing PVI.
  • Mandatory remapping at 6 months, with RFA used in phase 1 (n=30) and PFA in phase 2 (n=30).
  • 1-year follow-up with Holter monitoring; primary endpoints were PVI durability and arrhythmia recurrence.

Main Results:

  • PVI durability was comparable: 76% with RFA and 79% with PFA (P=0.77).
  • Overall PVI durability was 51% across both groups.
  • One-year freedom from recurrence was 70% with no significant difference between PFA and RFA (P=0.71).

Conclusions:

  • Pulsed field ablation offers PVI durability comparable to radiofrequency ablation in persistent AF.
  • A significant proportion of patients with durable PVI experienced recurrence, suggesting non-PV drivers.
  • Further investigation into non-PV mechanisms is warranted for persistent AF management.