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Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

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Published on: March 26, 2018

Contemporary approach and key considerations to asymptomatic aortic stenosis treatment

Marko Banović1,2, Bernard Iung3

  • 1Belgrade Medical School, University of Belgrade, Belgrade, Serbia.

Expert Review of Cardiovascular Therapy
|June 26, 2026
PubMed

Insights

Severe aortic stenosis (AS) treatment for asymptomatic patients is evolving. New guidelines suggest intervention for low-risk cases, but optimal strategies require further research and clinical trials.

Area of Science:

  • Cardiology
  • Valvular Heart Disease
  • Clinical Guidelines

Background:

  • Aortic stenosis (AS) is a prevalent and life-threatening valvular disease.
  • Management of asymptomatic severe AS remains under investigation.
  • Recent guidelines now include intervention for low-risk, asymptomatic severe AS patients.

Purpose of the Study:

  • To offer a rational, evidence-based approach for treating asymptomatic severe AS.
  • To guide clinical decisions for patients without additional adverse factors.
  • To review current evidence and identify knowledge gaps.

Main Methods:

  • Literature search of PubMed database.
  • Inclusion of original and review papers.
  • Keywords: aortic stenosis, asymptomatic, risk stratification, intervention.

Main Results:

  • Current ESC/EACTS guidelines for asymptomatic AS are a reasonable starting point.
  • Optimal intervention strategy requires further clarification due to patient and treatment heterogeneity.
  • Ongoing trials are expected to provide crucial new evidence.

Conclusions:

  • The optimal treatment strategy for asymptomatic severe AS needs further definition.
  • Randomized trials comparing TAVI and SAVR in middle-aged asymptomatic patients are essential.
  • Further research is vital to refine management of this patient group.
Abstract

Keywords:
Aortic stenosisasymptomaticclinical trialsinterventiontiming

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