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Published on: April 19, 2024

Molluscum Contagiosum Treatments in Children: A Systematic Review with Network Meta-Analysis

Letícia Rocha Campos1, Gisella Chiara Carpi2, Ana Beatriz Nardelli da Silva3

  • 1Department of Medicine, Universidade de Ribeirão Preto (UNAERP), Av. Costábile Romano, 2201, Nova Ribeirânia, Ribeirão Preto, SP, 14096-900, Brazil. ichbinleticiarochacampos@gmail.com.

Paediatric Drugs
|June 26, 2026
PubMed
Abstract

Insights

Salicylic acid + lactic acid, cantharidin, and potassium hydroxide show superior efficacy for treating molluscum contagiosum in children. This pediatric-specific network meta-analysis provides robust evidence for these treatments.

Area of Science:

  • Dermatology
  • Pediatrics
  • Evidence-Based Medicine

Background:

  • Molluscum contagiosum is common in children, affecting up to 11.5%.
  • Optimal pediatric treatment strategies remain unclear.
  • Previous reviews lacked pediatric-specific focus.

Conclusions:

  • Salicylic acid + lactic acid, cantharidin, and potassium hydroxide are effective treatments for pediatric molluscum contagiosum.
  • Treatment choice should consider efficacy, safety, and individual patient factors.
  • Further research is needed for single-study treatments.

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