Related Experiment Video
Updated: Jun 28, 2026

04:01
Revealing the Ferroptotic Phenotype of Medulloblastoma
Published on: March 15, 2024
Targeting ferroptosis halts graft deterioration in transplantation
1The Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Trends in Molecular Medicine
|June 26, 2026
Abstract
None:
Ischemia-reperfusion injury accelerates graft deterioration and limits the use of marginal donor organs. Recently, Veeckmans et al. showed that pharmacological ferroptosis inhibition preserves liver and lung graft function across porcine and human perfusion platforms, positioning lipid peroxidation-driven cell death as an actionable target in machine perfusion-era transplantation.