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Embodied Interoception Questionnaire (Intero-10): Development, Validation, and Application in People With Neuropathic
Ana Mércia Fernandes1, Vinicius D de Oliveira1, Carolina C Dos Santos1
1Pain Center, Department of Neurology, University of São Paulo, São Paulo, Brazil.
European Journal of Pain (London, England)
|June 26, 2026
Summary
The novel Intero-10 questionnaire measures embodied interoception, revealing that affective pain components are more stable than intensity. This tool aids in assessing chronic pain patients and those at risk.
Area of Science:
- Cognitive Neuroscience
- Psychology
- Pain Research
Background:
- Embodied interoception, the perception of bodily states, is a complex cognitive process.
- Pain influences interoceptive networks, suggesting subjective pain experience is linked to an individual's interoceptive profile.
Purpose of the Study:
- To develop and validate the Intero-10, a questionnaire assessing embodied interoception across trait interoceptive channels.
- To explore the relationship between embodied interoception and neuropathic pain features.
Main Methods:
- Developed and validated the Intero-10 questionnaire in healthy adults (n=381).
- Assessed trait-state interoceptive relationships using psychophysical tasks.
- Evaluated Intero-10's correlation with pain, mood, sleep, and quality of life in neuropathic pain patients (n=86).
Main Results:
- Trait and state interoceptive scores correlated for affective components (unpleasantness) but not intensity.
- The Intero-10 demonstrated good validity, internal consistency (Cronbach's α=0.81), and reliability (>0.75).
- Embodied interoception scores correlated with mood and quality of life, partially mediating pain interference's effect on quality of life.
Conclusions:
- The Intero-10 questionnaire offers a novel, structured method for assessing embodied interoception across sensory and affective dimensions.
- Quantifying embodied interoception in chronic pain provides insights into individual variability and potential therapeutic targets.
- Assessing specific embodied interoceptive channels can enhance the evaluation of individuals with chronic pain or those at risk.
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