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Updated: Jun 28, 2026

Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes
Published on: March 9, 2019
Coupled dual-channel memristors for hardware-native trustworthy Bayesian intelligence
Guowei Liu1,2, Jiaqi Ding2, Ziyu Wan1
1National Key Laboratory of Power Semiconductor and Integration Technology, College of Semiconductors (College of Integrated Circuits), Hunan University, Changsha, China.
Abstract:
Bayesian neural networks (BNNs) enable trustworthy edge intelligence by quantifying predictive uncertainty. However, hardware BNN implementations face a bottleneck: digital approaches suffer from high latency, while memristors are limited by the intrinsic coupling between their conductance state (mean) and stochastic noise (variance). Here we report a coupled dual-channel memristor (CDCM) based on an ion gel/ZnO heterostructure that breaks this fundamental trade-off. Utilizing vertical ion-gating to establish two tunable memristive channels, our device defines synaptic weight as the differential conductance between the two channels. This architecture enables the hardware-native orthogonal control over the synaptic weight mean (μ) and standard deviation (σ), allowing for the precise synthesis of decoupled Gaussian weights. We validate our approach with a hardware-calibrated BNN for multimodal human activity recognition, achieving 79.08% accuracy while reliably detecting unseen activities as out-of-distribution anomalies. This work provides a scalable, physics-driven paradigm for energy-efficient, inherently trustworthy probabilistic computing.
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