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Updated: Jun 28, 2026

Cross-Modal Multivariate Pattern Analysis
Published on: November 9, 2011
Cross-Subject Event-Related Potential Classification via Multi-View Based Contrastive Learning
Chaochen Chen1, Lugui Xia1, Jie Zhuang2
1Translational Research Center, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Computer Science and Technology, Tongji University, Shanghai, China.
Background:
Event-related potentials (ERPs) provide implicit feedback and error-correction signals that are valuable for brain-computer interfaces (BCIs). However, models trained on source-domain subject data are vulnerable to inter-subject variability and acquisition noise, which substantially degrades generalization to unseen subjects.
Objective:
We propose a multi-view contrastive learning domain generalization (MVCLDG) method to improve cross-subject generalization in ERP recognition by jointly exploiting discriminative feature extraction and domain-invariant representation learning.
Methods:
MVCLDG employs a multi-view feature-extraction module that fuses raw electroencephalography with phase information derived from the Hilbert transform via multi-scale inception blocks, thereby capturing both amplitude and phase features. The model then applies domain-alignment and contrastive-learning constraints to reduce distributional discrepancy across domains, compact within-class representations, and enlarge between-class separability. The approach was evaluated on a public Error-Related Negativity (ERN) dataset and a self-collected semantic-syntactic violation dataset; performance was assessed in cross-subject settings, and ablation and visualization analyses were conducted to probe the contributions of components and neurophysiological interpretability.
Results:
MVCLDG outperformed baseline and representative domain generalization methods in cross-subject ERP recognition without requiring additional target-domain adaptation. Ablation experiments confirmed the effectiveness of each component. Eigen-Class Activation Maps visualizations indicate consistency between the model-attended electrodes and known neurophysiological scalp patterns, supporting both the model's generalization mechanism and its biological interpretability.
Conclusions:
MVCLDG offers an effective strategy for integrating phase-aware multi-view feature mining with contrastive domain generalization, yielding improved and interpretable cross-subject ERP recognition. The method advances the feasibility of ERP-based closed-loop BCIs that generalize across users.
