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Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
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Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
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Related Experiment Video

Updated: Jun 30, 2026

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
06:18

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

Chikungunya Outbreak, Cuba, July 2025.

Melissa M Perez, Sonia Resik, Berta Maria Bello Rodriguez

    Emerging Infectious Diseases
    |June 28, 2026
    PubMed
    Summary

    Chikungunya virus transmission is confirmed in Cuba. The East/Central/South African genotype, linked to Brazil 2025 strains, was detected in patients and mosquitoes, indicating potential regional spread.

    Keywords:
    ChikungunyaCubaECSA genotypeoutbreakvector-borne infectionsviruses

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    Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus
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    Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

    Published on: May 31, 2020

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    Last Updated: Jun 30, 2026

    Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
    06:18

    Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

    Published on: March 13, 2018

    Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus
    10:35

    Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

    Published on: May 31, 2020

    Area of Science:

    • Medical Entomology
    • Virology
    • Epidemiology

    Background:

    • Chikungunya virus (CHIKV) poses a significant public health threat globally.
    • Vector-borne diseases require continuous surveillance for early detection and control.

    Purpose of the Study:

    • To confirm and characterize Chikungunya virus transmission in Perico, Matanzas Province, Cuba.
    • To identify the specific genotype of CHIKV and its potential source.

    Main Methods:

    • Detection of CHIKV RNA in human serum samples.
    • Identification of CHIKV in Aedes aegypti mosquito pools.
    • Genotyping of the detected CHIKV strains.

    Main Results:

    • Chikungunya virus transmission was confirmed in Perico, Cuba.
    • The East/Central/South African genotype of CHIKV was identified.
    • The detected genotype showed genetic relatedness to Brazil 2025 strains.
    • CHIKV was present in both human samples and local Aedes aegypti mosquitoes.

    Conclusions:

    • The findings confirm CHIKV circulation in Cuba.
    • The identified genotype suggests a potential link to recent outbreaks in the Americas.
    • Enhanced surveillance is crucial to monitor and prevent further spread of Chikungunya in the region.