Related Experiment Video
Updated: Jun 30, 2026

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
Published on: October 6, 2022
Sustained Remission of Ulcerative Colitis Achieved Following Antiretroviral Therapy in an HIV-Infected Patient: A
Kanako Ogasawara1, Takeo Naito1, Hideya Iwaki1
1Division of Gastroenterology, Tohoku University Graduates School of Medicine, Japan.
Abstract:
Ulcerative colitis (UC) and human immunodeficiency virus (HIV) infection represent opposing immunological states, and their coexistence poses distinct clinical challenges. Although several cases of UC in HIV-infected patients have been reported, remission induced by antiretroviral therapy is exceptionally rare in the literature. We describe a patient with UC complicated by HIV infection who achieved sustained remission following the initiation of antiretroviral therapy without any additional immunosuppressive therapy. Furthermore, we review the immunological interplay between UC and HIV infection and discuss their relevance to the pathophysiology and therapeutic strategies of the disease.
Related Concept Videos
Retrovirus Life Cycles
Drugs for Treatment of Ulcerative Colitis in IBD
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Inflammatory Bowel Disease II: Ulcerative Colitis
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
