Myocardial Perfusion and Fluorodeoxyglucose Uptake Patterns in Cardiac Sarcoidosis Stratified by Diagnostic Category
Daniel Sykora1, Jen Davison1, Gregorio Tersalvi2
1Mayo Clinic School of Graduate Medical Education.
Background:
18F-FDG PET/CT patterns in cardiac sarcoidosis (CS) across diagnostic subgroups are incompletely characterized.
Methods And Results:
We analyzed 221 patients with definite CS (DCS), probable CS with active extracardiac sarcoidosis (PCS-A), or probable CS without extracardiac involvement (PCS-N). DCS exhibited more severe perfusion defects than PCS-A and PCS-N. FDG uptake was similar in DCS and PCS-A, but lower in PCS-N. Abnormalities predominated in the basal/mid-septum and apical cap.
Conclusions:
Distinct PET patterns characterize CS diagnostic categories and support current diagnostic criteria.
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