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Published on: May 27, 2022
Serum Selenium Concentration in Neurosurgery Patients Receiving Parenteral Nutrition
Kenta Koketsu1, Kyongsong Kim1, Riku Mihara1
1Department of Neurological Surgery, Nippon Medical School Chiba Hokusoh Hospital.
Summary
Selenium deficiency is a concern in patients with acute neurologic disorders receiving enteral or parenteral nutrition. Measurement on admission is advised for older patients or those on prolonged tube feeding.
Area of Science:
- Clinical Nutrition
- Trace Elements
- Neurology
Background:
- Selenium is vital for physiological functions.
- Enteral and parenteral nutrition are common in acute neurologic disorders.
- Selenium deficiency incidence in these patients requires investigation.
Purpose of the Study:
- To determine the incidence of selenium deficiency.
- To assess selenium levels in patients with acute neurologic disorders receiving nutritional support.
- To identify risk factors for selenium deficiency in this population.
Main Methods:
- 39 patients receiving enteral/parenteral nutrition for ≥14 days were enrolled.
- Serum selenium levels were measured on admission, at 2 weeks, and 1 month.
- Low selenium was defined as <107 μg/L, with diagnosis based on clinical guidelines.
Main Results:
- Mean serum selenium was 119.9 μg/L on admission.
- A weak negative correlation was found between selenium levels and age.
- No patients had clinical symptoms of selenium deficiency; all deficiencies were subclinical.
Conclusions:
- Selenium measurement on admission is recommended for patients ≥75 years.
- Consider selenium monitoring for patients on hemodialysis or prolonged tube feeding.
- Selenium deficiency is a significant concern in neurosurgery patients with acute neurologic disorders requiring nutritional support.
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