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Related Experiment Videos

Explainable and clinically audited hybrid self-supervised framework for multi-class DFU classification and mobile

Abdullah Abdullah1,2, Muhammad Ateeb Ather1,2, Zulaikha Fatima3

  • 1Centro de Investigación en Computación (CIC), Instituto Politécnico Nacional (IPN), 07738, Mexico City, Mexico.

Scientific Reports
|June 28, 2026
PubMed
Summary

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This summary is machine-generated.

A new AI framework accurately classifies diabetic foot ulcers (DFUs) using self-supervised learning and image refinement. This technology offers high precision and explainability for improved DFU diagnosis and management.

Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Computer Vision

Background:

  • Diabetic foot ulcers (DFUs) require accurate classification for timely intervention.
  • Existing diagnostic methods may lack precision and explainability.
  • AI offers potential for enhanced DFU screening.

Purpose of the Study:

  • To develop and evaluate a Clinically Audited Hybrid Self-Supervised Framework for DFU classification.
  • To integrate domain-adaptive pretraining, spatial refinement, and classification for multi-class DFU diagnosis.
  • To assess the model's accuracy, explainability, and mobile deployment efficiency.

Main Methods:

  • Utilized SimCLR for self-supervised pretraining on DFU datasets.
  • Employed a U-Net refiner to enhance lesion boundary visibility.
Keywords:
Clinical validationDeep learningDiabetic foot ulcer (DFU)Edge computingEfficientNetExplainable artificial intelligence (XAI)Grad-CAMMobile healthSelf-supervised learning (SSL)SimCLRU-Net

Related Experiment Videos

  • Integrated an EfficientNet-B0 classifier for four-class DFU diagnosis (Normal, Abnormal, Ischemic, Infected).
  • Performed experiments on 24,000 DFU images with rigorous validation and testing splits.
  • Main Results:

    • Achieved high diagnostic performance: 99.98% accuracy, 99.91% precision, 99.92% recall, and 99.93% F1-score.
    • Demonstrated strong explainability with a mean IoU of 0.982 and 87.5% clinical interpretability.
    • Enabled efficient mobile deployment (TensorFlow Lite) with 180 ms/image inference and a ~150 MB app footprint.

    Conclusions:

    • The hybrid self-supervised framework provides high diagnostic precision and clinical interpretability for DFUs.
    • Efficient mobile deployment makes AI-driven DFU screening feasible for telemedicine and homecare.
    • This approach advances the potential of AI in managing diabetic foot complications.