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Updated: Jun 30, 2026

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
Published on: July 28, 2018
Association of cerebrovascular center volume with patient outcomes
Stacey Quintero Wolfe1, Justin R Mascitelli2, Kyle Fargen1
1Department of Neurosurgery, Wake Forest School of Medicine, Winston- Salem, NC, USA.
Insights
High procedural volumes in neurosurgery, including microsurgical and neuroendovascular interventions, are linked to better patient outcomes. High-volume centers and surgeons improve results for cerebrovascular diseases.
Area of Science:
- Neurosurgery
- Vascular Neurology
- Health Services Research
Background:
- Current guidelines emphasize both microsurgical and neuroendovascular expertise for cerebrovascular disease.
- Growing evidence suggests procedural volume significantly impacts patient outcomes in this field.
Purpose of the Study:
- To review the association between procedural volume and patient outcomes across various cerebrovascular diseases and interventions.
- To highlight the importance of high-volume centers and experienced providers in optimizing care.
Main Methods:
- Literature review of studies examining the relationship between procedural volume and patient outcomes.
- Analysis of data across multiple cerebrovascular conditions and treatment modalities.
Main Results:
- Higher procedural volumes are associated with lower mortality and improved patient safety for aneurysm clipping.
- High-volume centers and surgeons demonstrate better outcomes for cerebrovascular malformations and carotid endarterectomy.
- Mechanical thrombectomy and carotid stenting also show improved outcomes with increased procedural volumes.
Conclusions:
- Comprehensive cerebrovascular care requires experienced providers in high-volume centers for both hemorrhagic and ischemic conditions.
- The link between institutional/provider case volumes and better patient outcomes is well-established.
- Maintaining high-volume standards is crucial for ensuring quality in neurovascular care.
Abstract:
Current guidelines acknowledge the importance of both microsurgical and neuroendovascular expertise in the treatment of cerebrovascular disease. To achieve optimal care for these patients, it is becoming increasingly evident that procedural volumes impact patient outcomes. This is demonstrated across various cerebrovascular diseases.In this literature review, we demonstrate the association of volume with patient outcomes across multiple cerebrovascular disease states and interventions. Microsurgical aneurysm clipping remains essential even with the rise of endovascular therapy and mortality and patient-safety indicator events are clearly lower at high-volume centers for both ruptured and unruptured aneurysms. Likewise, patients undergoing surgery for cerebrovascular malformations and carotid endarterectomy have significantly better outcomes in high-volume centers by high-volume surgeons. Studies of mechanical thrombectomy and carotid stenting reinforce the association between higher procedural volumes, decreased mortality, and improved outcomes across various intervention modalities. The integration of neurocritical care has further improved outcomes, with specialized units demonstrating reduced mortality rates and lengths of stay.Modern cerebrovascular and stroke care necessitates comprehensive care by experienced providers in high-volume centers to optimize patient outcomes for both hemorrhagic and ischemic cerebrovascular disease. The relationship between higher institutional and provider case volumes and better patient outcomes is clearly delineated in the literature. Maintaining high-volume standards for endovascular and microsurgical cerebrovascular care can help ensure high-quality care across centers.
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