Related Experiment Video
Updated: Jun 30, 2026
04:22
Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
Published on: May 30, 2025
"Why not take that pill?": A Mixed-Methods Study of Gender, Risk Perception, and PrEP Uptake Among Drug-Involved
Dawn Goddard-Eckrich1, Srishti Meera Sardana2, Brandy F Henry3
1The Social Intervention Group, Columbia University, School of Social Work, 1255 Amsterdam Avenue, Room 801, NY, 10027, New York, USA. dg2121@columbia.edu.
AIDS and Behavior
|June 28, 2026
Summary
A couples HIV intervention improved condom use intentions among drug-using men on community supervision and their partners. The PACT intervention also increased female partners' pre-exposure prophylaxis (PrEP) use intentions.
Area of Science:
- Public Health
- HIV Prevention
- Behavioral Science
Background:
- Individuals under community supervision who use drugs have a higher risk of HIV infection.
- Understanding factors influencing pre-exposure prophylaxis (PrEP) acceptance is crucial for this population.
Purpose of the Study:
- To examine PrEP acceptance among community-supervised men who use drugs and their female partners using a mixed-methods approach.
- To evaluate the impact of a couples' HIV intervention (PACT) on PrEP willingness and condom use intentions.
Main Methods:
- A randomized controlled trial involving 394 participants randomized to either the PACT intervention or a control group.
- Qualitative interviews with 20 couples (40 individuals) to explore attitudes towards PrEP.
- Quantitative assessment of condom use and PrEP use intentions.
Main Results:
- The PACT group showed significantly higher intentions to use condoms with PrEP (64% vs. 53%, p=0.03).
- Female partners in the PACT intervention had stronger PrEP use intentions (aOR=2.85, p=0.02).
- Key factors influencing PrEP acceptance included infidelity concerns, substance use, HIV fears, low-risk perception, and medical mistrust.
Conclusions:
- Gender significantly influences PrEP acceptance in couples involved with the criminal legal system.
- Interventions should address gender differences, risk perception, and medical mistrust to improve PrEP uptake.
- The PACT intervention shows promise in enhancing HIV prevention behaviors within this high-risk population.
Related Concept Videos
02:07Blind Procedures
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which child was...
01:28Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
01:54The Placebo Effect
The placebo effect occurs when people's expectations or beliefs influence or determine their experience in a given situation. In other words, simply expecting something to happen can actually make it happen.
01:28Drug Therapy
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
01:28Dosage Regimens: Designs and Approaches
Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...