Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regression Toward the Mean01:52

Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...
Reason and Intuition01:37

Reason and Intuition

The human brain processes information for decision-making using one of two routes: an intuitive system and a rational system (Epstein, 1994; popularized by Kahneman, 2011 as System 1 and System 2, respectively). The intuitive system is quick, impulsive, and operates with minimal effort, relying on emotions or habits to provide cues for what to do next, while the rational system is logical, analytical, deliberate, and methodical. Research in neuropsychology suggests that the brain can only use...
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Delirium Leads to Poor In-Hospital and 90-Day Outcomes Among Patients With Acute Ischemic Stroke With and Without Intravenous Thrombolysis or Intraarterial Therapy.

Stroke (Hoboken, N.J.)·2026
Same author

Stroke Severity Mediates the Association Between Socioeconomic Disadvantage and Poor Outcomes Among Patients With Acute Ischemic Stroke.

Stroke (Hoboken, N.J.)·2026
Same author

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage.

Annals of clinical and translational neurology·2025
Same author

Postacute Discharge Destination and Major Adverse Cardiovascular Events Among Patients With Intracerebral Hemorrhage.

Stroke·2025
Same author

Examining Brain Structures and Cognitive Functions in Patients with Recovered COVID-19 Infection: A Multicenter Study Using 7T MRI.

medRxiv : the preprint server for health sciences·2024
Same author

Extraction of Radiological Characteristics From Free-Text Imaging Reports Using Natural Language Processing Among Patients With Ischemic and Hemorrhagic Stroke: Algorithm Development and Validation.

JMIR AI·2024

Related Experiment Video

Updated: Jun 30, 2026

Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke
05:30

Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke

Published on: October 10, 2025

Bayesian Thinking in Rehabilitation Research.

Farhaan S Vahidy1

  • 1Associate Vice President, Research and Chief Scientific Officer, TIRR Memorial Hermann, Houston TX.

American Journal of Physical Medicine & Rehabilitation
|June 29, 2026
PubMed
Summary

Bayesian statistical methods offer a complementary approach to frequentist methods in rehabilitation research. They provide direct probabilities of treatment benefit, aiding clinical decisions under uncertainty.

Keywords:
Bayesian analysisClinical decision makingRehabilitation Research

More Related Videos

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

A Tactile Automated Passive-Finger Stimulator (TAPS)
19:44

A Tactile Automated Passive-Finger Stimulator (TAPS)

Published on: June 3, 2009

Related Experiment Videos

Last Updated: Jun 30, 2026

Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke
05:30

Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke

Published on: October 10, 2025

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

A Tactile Automated Passive-Finger Stimulator (TAPS)
19:44

A Tactile Automated Passive-Finger Stimulator (TAPS)

Published on: June 3, 2009

Area of Science:

  • Rehabilitation Research
  • Biostatistics
  • Clinical Trial Analysis

Background:

  • Frequentist and Bayesian statistics represent distinct inferential frameworks.
  • Rehabilitation research often deals with modest treatment effects and clinical decisions under uncertainty.

Purpose of the Study:

  • To delineate conceptual distinctions between frequentist and Bayesian statistical paradigms.
  • To highlight the applicability of these statistical approaches within rehabilitation research.

Main Methods:

  • This perspective article compares inferential frameworks, focusing on interpretation over mathematical detail.
  • Illustrative examples include neuromodulation studies and a Bayesian reanalysis of the MISTIE III trial.

Main Results:

  • Frequentist methods (P values, confidence intervals) assess treatment effects indirectly but don't directly yield benefit probabilities.
  • Bayesian methods integrate prior knowledge with data to estimate posterior probabilities of treatment benefit.
  • Bayesian interpretation offers a nuanced view of uncertainty, moving beyond binary significant/nonsignificant outcomes.

Conclusions:

  • Bayesian methods enhance traditional analyses by offering interpretable probabilities of treatment benefit.
  • These methods support decision-making in uncertain clinical scenarios.
  • Bayesian conclusions are contingent on prior assumptions and do not supersede robust trial design or frequentist inference.