Medullary carcinoma of the thyroid as a laryngeal problem

A neuroendocrine secreting tumor, initially presenting as a laryngeal problem, is reported. Subglottic biopsy, first interpreted as paraganglioma, was finally diagnosed as medullary carcinoma of the thyroid. The complex testing required to arrive at an accurate diagnosis of this uncommon thyroid malignancy is discussed. The sparse occurrence of the neoplasm in the laryngologic field, as well as the necessity for differentiating it from other neuroendocrine tumors, bear consideration.