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[Impairment of retinal and choroidal blood flow autoregulation in preeclampsia]

E S Taskina1, A E Egorov2,3, V A Mudrov1

  • 1Chita State Medical Academy, Chita, Russia.

Vestnik Oftalmologii
|June 29, 2026
PubMed

Insights

Preeclampsia diagnosis can be improved by monitoring ocular blood flow. Impaired retinal blood flow in early pregnancy may signal future preeclampsia complications.

Area of Science:

  • Ophthalmology
  • Obstetrics
  • Cardiovascular Medicine

Background:

  • Preeclampsia is a major cause of maternal and perinatal mortality.
  • Early diagnosis is crucial for managing preeclampsia.
  • Ocular microcirculation offers insights into systemic endothelial function.

Purpose of the Study:

  • To analyze the association between impaired ocular blood flow regulation in preeclampsia and systemic complications.
  • To explore ocular hemodynamics as an early diagnostic marker for preeclampsia.

Main Methods:

  • Comprehensive data analysis of existing studies.
  • Focus on retinal and choroidal blood flow autoregulation.
  • Assessment of systemic hemodynamic and cerebrovascular complications.

Main Results:

  • Preeclampsia involves autoregulatory failure in ocular vessels, unlike normal vasodilation.
  • Retinal vasospasm in the first trimester can indicate preeclampsia.
  • Choroidal changes are complex and reflect systemic hemodynamic shifts.

Conclusions:

  • Impaired ocular vascular hemodynamics is an early indicator of systemic endotheliopathy in preeclampsia.
  • Monitoring ocular blood flow can help stratify risks for cerebrovascular and cardiovascular complications.

Keywords:
autoregulationcerebral blood flowchoroidocular blood flowpreeclampsiaretina

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