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Outcomes of coronary artery bypass grafting: insights from a single centre in South India
Sameer Mohammed1, Bineesh Kundoly Radhakrishnan1, Remya Sudevan2
1Department of CVTS, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala India.
Insights
Coronary artery bypass grafting (CABG) offers excellent 5-year survival and outcomes for multivessel coronary artery disease (CAD). This study highlights the effectiveness of CABG in the Indian population, providing crucial regional data.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Public Health
Background:
- Coronary artery bypass grafting (CABG) is the standard for multivessel coronary artery disease (CAD).
- Limited regional data exists on mid-term CABG outcomes, especially from South India.
Purpose of the Study:
- To evaluate 5-year survival, MACCE, and repeat revascularization rates after CABG in South India.
- To provide regional data on CABG outcomes for multivessel CAD patients.
Main Methods:
- Retrospective cohort study of 1634 patients undergoing isolated CABG (2003-2007).
- Data collected from institutional records; follow-up via outpatient visits, phone, mail.
- Kaplan-Meier curves used for survival and MACCE-free survival analysis.
Main Results:
- 5-year follow-up: 11.32% lost to follow-up.
- Cumulative 5-year MACCE rate: 5.87%.
- Overall 5-year survival: 85.74%; 12 patients required repeat revascularization.
- Symptom-free survival at 5 years: 75.56%.
Conclusions:
- CABG demonstrates excellent mid-term survival and outcomes for multivessel CAD at 5 years.
- The study provides valuable insights into CABG outcomes in the Indian population.
- Regional data is crucial for optimizing cardiovascular care strategies.
Purpose:
Coronary artery bypass grafting (CABG) has set the benchmark for managing multivessel coronary artery disease (CAD), providing superior mid-term outcomes. However, limited regional data, particularly from South India, exist on mid-term post-CABG outcomes. This study attempts to evaluate survival, major adverse cardiac and cerebrovascular events (MACCE), and freedom from repeat revascularisation over a 5-year follow-up period in patients undergoing CABG at a tertiary referral center.
Methods:
A retrospective cohort study was conducted on 1634 patients who underwent isolated CABG from January 2003 to December 2007. Data were collected from institutional records, and follow-up information was obtained via outpatient visits, phone calls, and mail. Overall survival and MACCE free survival were assessed using Kaplan-Meier curves. Statistical significance was determined using log-rank tests (p < 0.05).
Results:
Follow up was done for 5 years, after surgery. 11.32% of patients were lost to follow up at 5 years. The cumulative MACCE rate at 5 years was 5.87%. Overall survival at 5 years was 85.74%. Repeat revascularization was done for 12 patients. Symptom free survival dropped to 75.56% at 5 years (Fig. 1).
Conclusions:
CABG provides excellent mid-term survival, MACCE-free outcomes and freedom from repeat revascularisation in patients with multivessel CAD, at 5 years follow up. This study contributes valuable insights into CABG outcomes in the Indian population and underscores the importance of regional data for optimizing care strategies.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s12055-026-02205-9.
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