Local Injections of Fluorouracil for Eyelid Hordeolum
Mengzhe Qin1, Yutong Liang1, Xueshang Su1
1From the Department of Cosmetic Injection Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Plastic and Reconstructive Surgery. Global Open
|June 29, 2026
Summary
Local injection of diluted 5-fluorouracil offers a minimally invasive option for persistent eyelid nodules like hordeolum or chalazion. While effective for some, results varied, necessitating further research for optimal use.
Area of Science:
- Ophthalmology
- Dermatology
- Pharmacology
Background:
- Hordeolum and chalazion are common eyelid inflammatory conditions.
- Current treatments include warm compresses, antibiotics, and surgical drainage.
- Some patients experience persistent nodules or prefer non-surgical options for cosmetic reasons.

