Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ethics and Bioethics01:22

Ethics and Bioethics

Ethics is a philosophical study of moral actions. Ethics attempts to determine what is valuable for individuals and society. It examines the rational justification of moral judgments and analyzes what is morally just, fair, and right. Bioethics is a sub-discipline of applied ethics that analyzes the philosophical, social, and legal issues in life sciences and medicine. Ethical theories serve as a foundation for decision-making and represent the viewpoints from which people seek direction. They...
Ethical Dilemmas I01:17

Ethical Dilemmas I

Ethical dilemmas in nursing are of utmost importance, as they often arise from the tension between adhering to core ethical principles and the practical realities of healthcare delivery. These dilemmas require nurses to navigate complex situations where competing ethical considerations pull them in different directions.
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...
Ethical Issues01:27

Ethical Issues

Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
Ethical Dilemmas II01:30

Ethical Dilemmas II

Resolving an ethical dilemma in healthcare involves a systematic approach that considers every aspect of the issue, respecting both the patient's needs and values and the healthcare professional's ethical obligations. Here are potential steps to resolve an ethical dilemma:
Psychosurgery01:30

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Ethics in Research01:56

Ethics in Research

Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ethics and Regulation of Human Brain Organoid Research: Recommendations from the Asia Pacific Neuroethics Working Group.

Asian bioethics review·2026
Same author

Reconceptualizing Neural Authenticity: For Whom Is Digital Resurrection?

AJOB neuroscience·2026
Same author

Against "Flip" Thinking: Neural Organoids, Consciousness Inflation, and Evidence-Based Ethics.

AJOB neuroscience·2026
Same author

A philosophical reconstruction of moral distress: Its paradox and significance in healthcare practice.

Nursing ethics·2026
Same author

Epidemiology of Intensive Nutritional Interventions and Restraints in Hospitalizations for Anorexia Nervosa: Annual National Trends of the United States.

The International journal of eating disorders·2026
Same author

Beyond Explanation: Principlism as a Guiding Framework for Clinical Ethics Consultation.

The American journal of bioethics : AJOB·2026

Related Experiment Videos

Beyond consent: Reconstructing ethical justification in medical adaptive machine learning systems.

Keiichiro Yamamoto1, Makoto Udagawa2, Eisuke Nakazawa3

  • 1Department of Clinical Research Management, Center for Clinical Sciences, Japan Institute for Health Security, Tokyo, Japan.

Global Health & Medicine
|June 29, 2026
PubMed
Summary

Medical Adaptive Machine Learning Systems (MAMLS) continuously update using clinical data, challenging traditional research ethics. Current consent models face limitations, necessitating a shift towards public health ethics for MAMLS governance.

Keywords:
informed consentmedical artificial intelligencepublic health ethicspublic trustresearch ethics

Related Experiment Videos

Area of Science:

  • Medical Ethics
  • Artificial Intelligence in Healthcare
  • Machine Learning Governance

Background:

  • Medical Adaptive Machine Learning Systems (MAMLS) continuously learn from clinical data, blurring lines between therapy and research.
  • This necessitates re-evaluating their ethical classification and the applicability of informed consent requirements.

Purpose of the Study:

  • To analyze the ethical challenges posed by MAMLS, particularly concerning informed consent.
  • To explore the limitations of consent-centered ethics in the context of adaptive machine learning systems.
  • To propose an alternative ethical framework for governing MAMLS.

Main Methods:

  • Conceptual analysis of ethical frameworks for adaptive machine learning in clinical settings.
  • Examination of the implications of irreversibility and data bias in MAMLS on consent and autonomy.
  • Critique of traditional research ethics and proposal for a public health ethics approach.

Main Results:

  • Informed consent faces structural limitations due to the irreversibility of deep learning models and the "autonomy dilemma" caused by data bias.
  • Withdrawability, a key aspect of consent, is undermined, potentially transforming consent into institutional delegation.
  • Individual consent can paradoxically harm collective autonomy when data is unrepresentative or biased.

Conclusions:

  • Ethical justification for MAMLS requires moving beyond research ethics to a public health ethics framework.
  • Transparency, accountability, and participatory governance are crucial for building public trust in MAMLS.
  • Addressing MAMLS ethical challenges necessitates a broader societal approach beyond individual consent.