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Engineering a light-controllable fluorescent protein for peroxynitrite detection via genetic code expansion

Gloricelly M Roman Arocho1, Parthasarathi Das1, Sachin C Tennakoon1

  • 1Department of Chemistry, University of Nebraska - Lincoln Lincoln NE 68588 USA.

RSC Chemical Biology
|June 29, 2026
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Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...