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Triple-crush mechanism in multiple sclerosis-associated trigeminal neuralgia

Valentina Calistri1, Francesca Romana Pezzella2, Luca Prosperini3

  • 1Vigne Nuove-Kormed, Via Giovanni Pastrone 41, 00139, Rome, Italy.

Journal of Neurology
|June 29, 2026
PubMed
Abstract

No abstract available in PubMed .

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Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...

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