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Published on: October 10, 2025
Incidence, Mortality, and Premature Mortality From Neonatal Disorders in Eastern Sub-Saharan Africa, From 1990 to
Sebsibe Tadesse1,2, Bekam Yambo Jofa1, Gelgelo Wodessa1
1School of Public Health, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Introduction:
Neonatal disorders represent a significant global health challenge with a critical research gap in resource-constrained settings.
Objective:
This study aimed to estimate the incidence, mortality, and years of life lost (YLLs) from neonatal disorders in the Eastern Sub-Saharan Africa (ESSA) region from 1990 to 2023.
Methods:
The study used estimation methods from the Global Burden of Diseases 2023 study.
Results:
In the region, there were an estimated 300,042 new cases of neonatal disorders per 100,000 live births (95% UI: 293,808, 305,567), 21,889 deaths per 100,000 live births (95% UI: 20,447, 22,993), and 1.9 million YLLs per 100,000 live births (95% UI: 1.8, 2.1) in 2023. There was a considerable decline in the rates between 1990 and 2023.
Conclusion:
The ESSA region experienced considerably high rates of incidence, mortality, and YLLs from neonatal disorders. Targeted interventions, including primary prevention and quality maternal and newborn health services should be implemented.
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